Eating Habits of College Students Research Paper

Eating Habits of College Students - Research Paper Example Also, it demonstrates how adequate understanding of consequences of poor eating habits can improve the health of the students and the entire nation. 1. Research question(s), rationale and qualifications, This study aims to answer various issues relating to eating habit of the college students. For example, how does food quality of campus cafe affect eating habits of the college student? What factors influence the eating habit of the college students? Is there a relationship between campus life and eating students eating habit? Does poor eating habit among the college students have any effect on their health? What is the link between the level of health dietary awareness and students eating habit? 2. Outcomes and impact The rate of overweight and obesity in the United States has been rising at an alarming rate as well as the prevalence of lifestyle diseases such as cardiovascular, diabetes and so on. Various studies have shown that the most affected population are those between the age of 18 and 29 years, and an unfortunate majority of these are the college, students. Also, about 36% of the college students are either overweight or obese (Farrell, 2010). The menace of overweight or obesity among the college students has been contributed by unhealthy eating habits. The college environment has also made a significant influence on the eating habits of the students because of the availability of large portions of high calorie and fat foods as well as buffet style cafeteria (Deshpande et al., 2009).

Chapter 5 Reaction Essay Example | Topics and Well Written Essays - 500 words

Chapter 5 Reaction - Essay Example I am now more aware that precautions should be observed when communicating with others, especially those people from diverse cultural orientations or those who do not belong to the same generation to prevent misunderstanding. The authors’ style of using diverse real life scenarios to explain points of contention provided clear illustration and support to the arguments. Examples in the form of stories, incidents, and funny communication scenarios reinforce meanings to the lessons that the author aimed to impart. The value of the information in the chapter is measured in terms of its applicability to one’s personal life. As I live in a Western culture where people are more open, frank, and honest in terms of verbal communication, I have accepted and adapted the practice of being direct but likewise vigilant in using frames and idioms depending on the situation and the person I am talking to. Likewise, not because I live in the United States, does it necessarily mean that I have to impose the American culture and way of live to other people from diverse racial and cultural background. The article assisted in guiding me towards using proper decorum and to be more vigilant in exerting appropriate efforts in learning and being aware of critical acceptable and unacceptable behavior in terms of communication patterns and expressions.

Graphic design Essay Example for Free

Graphic design Essay I have been surrounded with art my whole life. My aunt is a photography major and my father started out in graphic design but now does more of the business side than creative. I grew up in a home that had a love for art. When I was little I used to sit for hours and hours and watch my dad work on his projects. I just loved watching how he created the beautiful picture and wanted to learn how I could do it too. I took art classes in elementary and junior high school and loved being able to create pictures with pencil, oil pastels, paint, or create a vase with broken pieces of glass. Once I got to high school I took digital photography, drawing, web design, and interior design and loved it all. I knew graphic design was what I wanted to do when I looked at all the classes required for the major and couldn’t wait to take all of them and learn all that I could. The beauty of art has always attracted me and I have always loved being able to create it myself. Sometimes I kind of struggle with the whole inspiration or â€Å"what do I draw† thoughts, but with graphic design there is more of a need where a client needs a logo, or a web page, or play bill to be designed. There is already the need and I am here to fulfill that need with my creative ideas and it has more of a purpose than to just make somebody feel something. It is to catch the viewers’ eye and intrigue them to come to your event or buy your product. I love being able to help people. Knowing that I can both create art and help someone with graphic design is just the perfect fit for me.

Solid Dispersion System in Drug Delivery

Solid Dispersion System in Drug Delivery The oral route remains the preferred route of drug administration due to its convenience, good patient compliance and low medicine production costs. In order for a drug to be absorbed into the systemic circulation following oral administration, the drug must be dissolved in the gastric fluids. The active pharmaceutical ingredient in a solid dosage form must undergo dissolution before it is available for absorption from the gastrointestinal tract.1 Currently, approximately 40% of the marketed immediate release (IR) oral drugs are categorized as practically insoluble ( 1.1 Biopharmaceutics classification system The Biopharmaceutical Classification System (BCS) was introduced in the mid-1990s to classify the drug substances with respect to their aqueous solubility and membrane permeability. BCS is a useful tool for decision-making in formulation development from a biopharmaceutical point of view. Solubility improvement strategies are required for Class II and Class IV drugs. 1.2 Approaches to improve the solubility or to increase the available surface area for dissolution Physical modifications Particle size Micronization Nanosuspensions Modifications of the crystal habit Polymorphs Pseudopolymorphs (including solvates) Complexation/solubilization Use of surfactants Use of cyclodextrins Drug dispersion in carriers Eutectic mixtures Solid dispersions (non-molecular) Solid solutions Chemical modifications Soluble prodrugs Salts 1.3 Solid Dispersions The term solid dispersion refers to a group of solid products consisting of at least two different components, generally a hydrophilic matrix and a hydrophobic drug. The matrix can be either crystalline or amorphous. The drug can be dispersed molecularly, in amorphous particles (clusters) or in crystalline particles.7 Much of the research that has been reported on solid dispersion technologies involves drugs that are poorly water-soluble and highly permeable to biological membranes as with these drugs dissolution is the rate limiting step to absorption. Hence, the hypothesis has been that the rate of absorption in-vivo will be concurrently accelerated with an increase in the rate of drug dissolution. Therefore, solid dispersion technologies are particularly promising for improving the oral absorption and bioavailability of BCS Class II drugs. 1.3.1 Types of solid dispersions On the basis of release mechanisms and molecular arrangement in the matrix, solid dispersions are distinguished into following types9: A. Simple eutectic mixture: Eutectic mixture is prepared by rapid solidification of fused melts of two components that show a complete liquid miscibility with negligible solid-solid solubility. It involves loose atomic or molecular interaction and not on the formation of chemical bonds. When the eutectic mixture is exposed to gastrointestinal fluids, both the poorly soluble drug and the carrier may simultaneously crystallize out as a very small particles result in an increased the surface area and improved dissolution and absorption of the drug. B. Solid solution: A solid solution represents a homogenous one phase system, where the solid solution is dissolved in a solid solvent and the two components crystallize together. The solid solution achieves faster dissolution than a eutectic mixture because the drug particles in a solid solution are reduced to molecular size and dissolution of the drug takes place in the solid state prior to the exposure to the liquid medium. C. Glass solution: It is a homogenous glassy system in which a solute dissolves on glassy solvent results in increased dissolution and absorption of the drug. It is characterized by a transparency and brittleness below the glass forming temperature. Glass solution is a metastable and the strength of the chemical bonding is much less as compared to solid solution. Therefore, the release of the drug was found to be faster than a solid solution. D. Amorphous precipitations in crystalline carrier: An amorphous form of a drug produces faster dissolution rate. The drug may precipitate out in an amorphous form in a crystalline carrier from solid dispersions prepared by melting or solvent method. A strong interaction between the drug and carrier resulting in the formation of channels within the matrix seems to be a possible mechanism for improved dissolution of the drug. E. Compound or complex formation: The formation of a complex between the drug and the carrier may either decrease of increase the dissolution and the absorption rate of the drug. The formation of soluble complex with low association constant resulted in increased rate of dissolution and absorption. The enhancement in dissolution rate of the drug can be ascribed to An increasing solubility of the drug because of its amorphous state or small particle size (Kelvins law)9,10 An increased surface area available for drug dissolution because of the small size of the drug particles11,12 An improvement in wetting of the drug caused by the hydrophilic carrier13,14 1.3.2 Advantageous properties of solid dispersions Management of the drug release profile using solid dispersions is achieved by manipulation of the carrier and solid dispersion particle properties. Parameters such as carrier molecular weight and composition, drug crystallinity and particle porosity and wettability, when successfully controlled, can produce improvements in bioavailability.16 a. Particles with reduced particle size: Molecular dispersions, as solid dispersions, represent the last state on particle size reduction, and after carrier dissolution the drug is molecularly dispersed in the dissolution medium. Solid dispersions apply this principle to drug release by creating a mixture of a poorly water soluble drug and highly soluble  carriers. A high surface area is formed, resulting in an increased dissolution rate and consequently, improved bioavailability. b. Particles with improved wettability: Strong contribution to the enhancement of drug solubility is related to the drug wettability improvement in solid dispersions. It was observed that even carriers without any surface activity, such as urea improved drug wettability. Carriers with surface activity, such as cholic acid and bile salts, when used, can significantly increase the wettability properties of drugs. Moreover, carriers can influence the drug dissolution profile by direct dissolution or co-solvent effects. c. Particles with higher porosity: Particles in solid dispersions have been found to have a higher degree of porosity. The increase in porosity also depends on the carrier properties, for instance, solid dispersions containing linear polymers produce larger and more porous particles than those containing reticular polymers and, therefore, result in a higher dissolution rate. The increased porosity of solid dispersion particles also hastens the drug release profile. d. Drugs in amorphous state: Poorly water soluble crystalline drugs, when in the amorphous state tends to have higher solubility. The enhancement of drug release can usually be achieved using the drug in its amorphous state, because no energy is required to break up the crystal lattice during the dissolution process. 1.3.3. Carriers used in solid dispersions Many carriers of natural, semi-synthetic and synthetic types are being used which include natural carbohydrates, semi-synthetic and synthetic hydrophilic polymers. S.No:  1 Nature of carrier:  Sugars Name of the carrier:  Dextrose, sorbitol, sucrose, fructose,maltose,galactose, xylitol, mannitol S.No:  2 Nature of carrier:  Acids Name of the carrier:  Citric acid, tartaric acid and succinic acid S.No:  3 Nature of carrier:  Polymorphic materials Name of the carrier:  Polyvinyl pyrrolidone (PVP), polyethylene glycols, hydroxyl propylmethylcellulose (HPMC), guargum, xanthan gum, sodium alginate, methyl cellulose, pectin, hydroxyl ethyl cellulose (HEC), hydroxyl propyl cellulose (HPC) and dextrins. S.No:  4 Insoluble or enteric Nature of carrier:  polymer Name of the carrier:  Hydroxy propyl methyl cellulosepthalate, eudragit RL, eudragit L 100, eudragit S100, eudragit RS. S.No:  5 Nature of carrier:  Surfactants Name of the carrier:  Polyethylene stearate, poloxamer 188, tweens and spans. S.No:  6 Nature of carrier:  Miscellaneous Name of the carrier:  Nicotinic acid, succinamide, dextrans, gelatin, poly vinyl alcohol, urea, cyclodextrins, skimmed milk etc., Table 1.2 Various carriers used in solid dispersions 1.3.4. Preparation techniques of solid dispersions The following are the major processes for the preparation of solid dispersions. A. Solvent evaporation method: In this method, the physical mixture of two components is dissolved in a common solvent and followed by the evaporation of solvent. The advantages of this method are low temperature requirements for the preparation of dispersion and thermal decomposition of drugs and carriers can be prevented. The higher cost of production, incomplete removal of solvent, adverse effects of solvent on the chemical stability of the drug and selection of common solvent are the drawbacks of this method. B. Melting method (Fusion method): The physical mixture of drug and water- soluble carrier was heated to melt and the molten mixture was then cooled and solidified mass was crushed, pulverized and sieved. The melting point of a binary system depends on its composition and proper manipulation of drug carrier ratios. Decomposition should be avoided due to fusion time and the rate of cooling. C. Kneading method: The physical mixture of drug and carrier were triturated using small quantity of organic solvent and water mixture, usually alcohol and water (1:1v/v). The slurry is kneaded for 45 minutes and dried at 45 °C. The dried mass is pulverized and sieved through sieve no. 60 and the fraction was collected. The advantages of this method are low temperature requirements for solid dispersion preparation and usage of organic solvent is less. This method of preparation avoids thermal degradation of drug and employs less quantity of organic solvents. D. Melting solvent method: This method involves dissolving the drug in a suitable solvent and the incorporation of the solution directly into the molten carrier. This method possesses the advantages of both solvent and melting methods. E. Supercritical fluid methods: Supercritical fluid methods are mostly applied with carbon dioxide (CO2), which is used as either a solvent for drug and matrix or as an antisolvent. This technique consists of dissolving the drug and the carrier in a common solvent that is introduced into a particle formation vessel through a nozzle, simultaneously with CO2. When the solution is sprayed, the solvent is rapidly extracted by the SCF, resulting in the precipitation of solid dispersion particles on the walls and bottom of the vessel. This technique does not require the use of organic solvent and since CO2 is considered environmentally friendly, this technique is referred to as solvent free. This technique is known as Rapid Expansion of Supercritical Solution (RESS). F. Lyophilization/ Freeze Drying: This technique is an alternative to the solvent evaporation method. Here the drug and carrier are dissolved in common solvent, frozen and sublimed to obtain a lyophilized molecular dispersion. G. Melt agglomeration process: This technique is used to prepare solid dispersion where a binder acts as a carrier. The solid dispersion is prepared by heating binder, drug and excipient to a temperature above the melting point or spraying the dispersion of drug in the molten binder on the heated excipients using a high shear mixer. The effect of binder type, method preparation and particle size are the critical factors influencing the solid dispersion preparation by this method. These parameters results in various dissolution rates, mechanism of agglomerate formation and growth, agglomerate size and distribution. 1.3.5. Limitations of solid dispersion systems: Problems limiting the commercial application of solid dispersions are: Laborious and expensive method of preparation. Reproducibility of physico-chemical characteristics. Difficulty in incorporating into the formulation of dosage forms. Crystallization of the amorphous drug in the dispersion. Poor scale up of manufacturing process and physical and chemical stability of drug and the vehicle. 1.4 FDTs: Fast-disintegrating and fast-dissolving tablets are becoming popular as novel delivery systems for drug administration. They are more convenient for children, elderly patients, patients with swallowing difficulties, and in the absence of potable liquids. The most desirable formulation for use by the elderly is one that is easy to swallow easy to handle. Taking these requirements into consideration, attempts have been made to develop a fast-disintegrating tablet. Since such a tablet can disintegrate in only a small amount of water in the oral cavity, it is easy to take for any age patient, regardless of time or place. For example, it can be taken anywhere at anytime by anyone who do not have easy access to water. It is also easy to dose the aged, bedridden patients, or infants who have problems swallowing tablets and capsules. Recently, many companies have researched and developed various types of fast-disintegrating dosage forms.18 These tablets display a fast and spontaneous de-aggregation in the mouth, soon after the contact with saliva, though they can be handled or extracted from the package without alteration. The active agent can thus rapidly dissolve in the saliva and be absorbed through whatever membrane it encounters, during deglutition, unless it is protected from pre-gastric absorption. To fulfill these requirements, tablets must be highly porous, incorporating hydrophilic excipients, able to rapidly absorb water for a rapid deaggregation of the matrix. Different technological techniques, such as freeze drying or molding or direct compression are currently employed to prepare the formulations of this type present on the pharmaceutical market. 1.4.1 Advantages of Fast Disintegrating Drug Delivery System (FDDS) 19,20 Ease of administration to patients who refuse to swallow a tablet, such as pediatric and geriatric patients, mentally ill, disabled and uncooperative. Convenience of administration and accurate dosing as compared to liquids. No need of water to swallow the dosage form, which is highly convenient feature for patients who are traveling and do not have immediate access to water. Good mouth feel property of FDDS helps to change the basic view of medication as bitter pill, particularly for pediatric patients. Ability to provide the advantages of liquid medication in the form of solid preparation. Rapid dissolution of drug and absorption, which may produce rapid onset of action. Some drugs are absorbed from the mouth, pharynx and oesophagus as the saliva passes down into the stomach; in such cases bioavailability of drugs is increased. Pregastric absorption can result in improved bioavailability and as a result of reduced dosage, improved clinical performance through a reduction of unwanted effects. 1.4.2 Approaches for fast disintegrating tablets A. Patented technologies Currently, four fast-dissolving/disintegrating technologies have reached the U.S. market: Zydis (R.P. Scherer, Inc.) WOWTAB (Yamanouchi Pharma Technologies, Inc.) OraSolv (Cima Labs, Inc.) DuraSolv (Cima Labs, Inc.) B. Three others are available outside the U.S. Flash Dose (Fuisz Technologies, Ltd.), Flash tab (Prographarm Group), OraQuick (KV Pharmaceutical Co., Inc.) Nanocrystal Technology C. Conventional technologies Freeze -drying or lyophilization Tablet Molding Direct compression Spray drying Sublimation Mass extrusion Direct compression It is the easiest way to manufacture tablets. Conventional equipment, commonly available excipients and a limited number of processing steps are involved in direct compression. Also high doses can be accommodated and final weight of the tablet can easily exceed that of other production methods. Directly compressed tablets disintegration and solubilization depends on the single or combined action of disintegrates, water soluble excipients and effervescent agent. Disintegrate efficacy is strongly affected by tablet size and hardness. Large and hard tablets have a disintegration time more than that usually required. As consequences, products with optimal disintegration properties often have medium to small size and /or high friability and low hardness. Breakage of tablet edges during handling and tablet rupture during the opening of blister, all results from insufficient physical resistance. Disintegrants have a major role in the disintegration and dissolution process of mouth dissolving Tablets made by direct compression. To ensure a high disintegration rate, choice of suitable type and an optimal amount of disintegrant is important. Other formulation components such as water soluble excipients or effervescent agents can further enhance dissolution or disintegration properties. But the main drawback of using effervescent excipients is their highly hygroscopic nature. The understanding of disintegrant properties and their effect on formulation has advanced during the last few years, particularly regarding so called superdisintegrants. Disintegration efficiency is based on a force equivalent concept, which is the combined measurement of swelling force development and amount of water absorption. Force equivalent expresses the capability of disintegrant to transform absorbed water into swelling force. The optimization of tablet disintegration was defined by means of disintegrant critical concentration. Below this concentration, the tablet disintegration time is inversely proportional to disintegrate concentration and above that disintegration time remains approximately constant or even increases. The simultaneous presence of disintegrate with a high swelling force called disintegrating agent and substances with low swelling force ( starch, cellulose and direct compression sugar) defined as, swelling agent was claimed to be a key factor for the rapid disintegration of the tablet, which also offers physical resistance. 1.4.3 Mechanism of tablet disintegration and water absorption When mouth dissolving tablets placed in the mouth, upon contact with saliva the tablet disintegrates or dissolve instantaneously. The mechanisms involved in the tablet disintegration mechanisms are Swelling Wicking (capillary) Deformation Particle repulsive forces Chemical reaction (acid base reaction) a. Swelling Not all disintegrates swell in contact with water swelling is believed to be a mechanism in which; certain disintegrating agents (like starch) impart their disintegrating effect. By swelling in contact with water, the adhesiveness of other ingredients in a tablet is overcome causing the tablet to disintegrate. b. Wicking (porosity and capillary action) Effective disintegrants that do not swell are believed to impart their disintegrating action through porosity and capillary action. Tablets porosity provides a way for the penetration of fluid into tablets. The disintegrants particles (with cohesiveness and compressibility) themselves act to enhance porosity and provide these capillaries into the tablets. Liquid is drawn up or wicked into these ways by capillary action and rupture the inter-particulate bonds causing the tablet to break into small parts. c. Deformation Starch grains are generally thought to be elastic in nature that is the grains that are deformed under pressure will return to their original shape when that pressure is removed. But, with the compression forces involved in tabletting, these grains are permanently deformed and are said to be energy rich with these energies being released upon exposure to water, that is the ability for starch to swell is higher in energy rich starch grains than in starch grains that have not been deformed under pressure. It is believed that no single mechanism is responsible for the action of most disintegrants. But rather, it is more likely the results of interrelationships between these major mechanisms. d. Due to disintegrating particle/particle repulsive forces: Another mechanism of disintegration attempts to explain the swelling of tablets made with non-swellable disintegrants. Guyot-Hermann has proposed a particle repulsion theory based on the observation that nonswelling particle also causes disintegration of tablets. The electric repulsive forces between particles are the mechanism of disintegration and water is required for it. Researchers found that repulsion is secondary to wicking. e. Chemical reaction (acid base reaction) Disintegration of tablet included with citric acid and tartaric acid along with the sodium bicarbonate, sodium carbonate, potassium carbonate; these react in contact with water to liberate carbon dioxide that disrupts the tablet. Name of the Product:  Imodium Lingual Active Ingredients:  Loperamide hydrochloride Dose:  2 mg Name of the Product:  Pepcidin Rapitab Active Ingredients:  Famotidine Dose:  20mg and 40 mg Name of the Product:  Mosid MT Active Ingredients:  Mosapride citrate. Dose:  2.5mg and 5mg Name of the Product:  Calritin Reditabs Active Ingredients:  Loratadine Dose:  10 mg Name of the Product:  Nimulid MD Active Ingredients:  Nimesulide Dose:  50mg and 100mg Name of the Product:  Zyrof Meltab Active Ingredients:  Rofecoxib Dose:  50 mg Name of the Product:  Feldene Melt Active Ingredients:  Piroxicam Dose:  10mg and 20 mg Name of the Product:  Maxalt-MLT Active Ingredients:  Rizatriptan Dose:  5mg and 10 mg Name of the Product:  Pepcid RPD Active Ingredients:  Famotidine Dose:  20mg and 40 mg Name of the Product:  Zyprexa Zydis Active Ingredients:  Olanzapine Dose:  5mg, 10mg, 15mg and 20 mg Name of the Product:  Zofran ODT Active Ingredients:  Ondansetron Dose:  4 mg and 8 mg Name of the Product:  Remeron Soltab Active Ingredients:  Mirtazepine Dose:  15mg, 30mg and 45 mg Name of the Product:  NuLev Active Ingredients:  Hyoscyamine sulfate Dose:  0.125 mg Table 1.3 Marketed fast disintegrating tablets Piroxicam, a non-steroidal anti inflammatory agent, belonging to BCS class II is widely used as a first line drug in the symptomatic relief of rheumatoid arthritis and osteoarthritis. Its low aqueous solubility has to be overcome through formulation strategies. Skimmed milk can be used as a drug carrier as it is inexpensive, easily available, biodegradable, and does not exhibit toxicity problems as experienced with PEG and PVP.24-26 Polymers  as  carriers  also  have  limitations  in  enhancing  Ã‚  the  Ã‚  solubility  of poorly  soluble drugs  due to  their  high viscosity. So the use of skimmed milk in the formulation of the SD of the drugs with limited aqueous solubility may be a potential and cost effective way to overcome the problem.27 Skimmed milk is a colloidal suspension of casein micelles, globular proteins and lipoprotein particles. The principal casein fractions are a-s1, a-s2, b-casein and k-casein. b-casein is amphiphilic and acts as a detergent molecule with surfactant property. The milk also contains whey proteins with principle fractions of the b-lacto globulin, a-lactalbumin, bovine serum albumin and immunoglobulins. These molecules were found to be surface active with a superior solubility than caseins.28 Aminoacids have been suggested either as additives in peroral application or in the form of aminoacid salts to reduce gastrointestinal disorders arising due to piroxicam like NSAIDs. The surface active agents and amino acid content are expected to be the reason for increased permeation of the drug from the solid dispersion.29,30

The 10 Most Sacred Places in the World

The 10 Most Sacred Places in the World 10 Most Sacred Places in the World Faith is the driving power for billions of people around the world. Regardless of the religion or faith you belong to, there are sacred places for every kind of people throughout the world. After going through many of such places and locations around the world, we have come up with what we think are top 10 in our mind regardless of the order. Below is a list these sacred places: 1-Masjid Al Haram-The Kaaba, Makkah, Saudi Arabia Masjid Al Haram is considered the most sacred place for Muslims. This place holds a significant value in the history of Islam and is the birth place and home to the last prophet and the most important and influential figure in Islam, the beloved Muhammad (PBUH). This place is significant for other reasons too, like Hajj- the biggest annual gathering of over 16 million Muslims from all over the world conducted to show unity and love to the one and only God- ALLAH. This place is surrounded by mountains and the ambiance and the atmosphere here exudes peace and tranquility. Praying-in and visiting this place really reinvigorates faith in your mind and soul and the feeling you get here is nothing you would have ever experienced in your entire life. Visit: http://www.beautifulmosque.com/Masjid-al-Haram-Night-View-Saudi-Arabia 2-Cenote Sagrado, Mexico Cenote is basically an underground water reservoir, and the Mayan people considered these to be very important for the sustenance of life, essentially due to water. Cenote Sagrado is one such cenote which is considered to be a sacred place for these people. This cenote is created from natural limestone, and is located in the Yucatan Peninsula. It is believed that unlike normal cenotes that provided people with daily life necessities like drinking and bathing, this cenote was used for ceremonies and special purposes like sacrificing children and women in the times of drought to please Chac, who was believed to be the God of Rain by the Mayans. The place is so beautiful and peaceful that you’d want to stay there forever. Visit: http://travel.prwave.ro/the-cenote-at-chichen-itza/ 3-Shwedagon Pagoda, Myanmar Shwedagon Pagoda is named by many travelers and tourists as the sacred place to visit. This beautiful monument of Gold is located some 100 yards over Rangoon, the largest and the former capital city of Burma. This location especially comes to life at the evening and night times and is famous in Buddhist people due to it being home to Buddha’s remnants. http://www.ursulasweeklywanders.com/culture/the-heart-of-myanmar-shwedagon-pagoda-yangon/ 4-Crater Lake, Oregon This is a beautiful fresh water lake that is located in the central region of South Oregon. It is a crater that has been considered sacred by the local Klamath tribe for centuries and is believed to have come into existence as result of an explosion in Mount Mazama some 8000 years ago. The place is covered with lush green plantation and the beautiful lake water reflects the sky to turn into a deep blue color. The result is a stunning scenery, a wonder that eyes just cannot let go of, the serenity and peacefulness of the location just captivates your imagination like few other places can. Visit: http://nexttriptourism.com/crater-lake-tourism-in-oregon/ 5-Hagia Sophia, Turkey Hagia Sophia can be considered as one of the most visited sacred places by tourists on Earth. This sacred place, unlike the rest is an architectural marvel, and reflects one of the finest pieces of craftsmanship you would ever encounter in your life. The most unique and differentiating fact about this place is that although it is a sacred place for Muslims in particular, but it attracts tourists from all over the world regardless of their beliefs and religions. Visit: http://nexttriptourism.com/hagia-sophia-is-a-unique-turkey/ 6-Ghats of Varanasi, India Ghat can be understood as a riverside place or the place on the river banks where one can sit or change before entering into the river. Varanasi is a sacred city of India and the several Ghats present on riverside in this famous city provides for hundreds and thousands of believers with bathing opportunities, the place to meditate or even an opportunity to say the final ceremony of their loved ones. The setting sun on this beautiful river is also a sight which will leave you speechless and in complete awe. Visit: http://www.hindugodwallpaper.com/wallpaper-59-101.html 7-Spanish Synagogue, Czech Republic If you are a Jew and happen to live in Europe, then you cannot miss to visit this sacred place. This is probably one of the most beautiful Synagogues in the Entire Europe, or better yet in the entire world. Located in the beautiful city of Prague, this synagogue is loaded with Fascinating ancient drawings, designs and beautiful architecture that overwhelms you with its presence, and the calm and quite atmosphere revives the faith from within. Visit: http://jbuff.com/shul%20prague%20spanish_synagogue.htm 8-Mount Kailash, Tibet This is probably the most beautifully dangerous sacred destination on our list. Mount Kailash is of immense importance for more than one religion, it is considered a holy place in religions like Hinduism, Buddhism, Jainism and the religion of Bon. Annual trip to this wonderful and sacred mountain is made by many thousands who believe in its sacredness, but the road to the location is a very tricky one and you might need some assistance if you’re visiting for the first time. Visit:http://www.mountainsoftravelphotos.com/Kailash/Inner%20Kora/slides/33%20Nandi%20From%20Above%20Nandi%20Pass%20On%20Mount%20Kailash%20Inner%20Kora%20Nandi%20Parikrama.html 9-Vatican  City Set foot in the world’s only carbon neutral state, the Vatican City is as beautiful as it is sacred. It is home to the Pope and presents some of the most beautiful and the scarcest pieces of art and backdrops you can find in Rome. The city is absolutely full of lush green gardens and the atmosphere of the city just brings about the surge of emotions that are hard to feel in other cities of the world. Visit: http://www.airpano.com/360Degree-VirtualTour.php?3D=Vatican 10-Jerusalem Jerusalem is probably one of the oldest sacred places to have existed on this planet. Bearing its significance in some of the biggest religions in the world, it is a sacred and holy place for Muslims, Jews and Christians since thousands of years. Many battles have been fought amongst Christians, Jews and Muslims in the history over this great city and it still to this day is the most important city for Muslims after Makkah and Madinah. The mere history and the culture that this holy land presents is enough to attract millions from all over the Globe annually. Visit: http://sharingjerusalem.org/

What is in yours? :: science

What is in yours? From the moment parents bring their new baby home from the hospital, they watch their baby's progress, anticipating every inch of growth and each new developmental milestone along the way. But what exactly are they watching for and how do parents know if their child is growing properly? Growth is the various physical and developmental milestones that most children reach during each age level. Physical growth, which is generally measured in terms of height, weight and head growth, is also monitored carefully. This includes increases in height and weight as well as development in cognitive, language, and social skills. Hair grows; teeth come in, come out, and come in again; and eventually puberty hits. It's all part of the growth process. The first year of an infant's life is a time of astonishing change. During this time, a baby will grow rapidly and achieve major developmental milestones, such as taking first steps or maybe even saying a few first words. On average, babies grow 10 inches in height while tripling birth weight by their first birthday. Beginning in infancy, a child will visit a doctor for regular checkups. At each of these visits, the doctor will record the child's height and weight on a growth chart. This chart shows the doctor and parents how the child's height and weight compare to that of other children the same age. This can help your child's doctor determine whether your child is growing at an appropriate rate or whether there might be any problems. After age 1, a baby's growth in length slows considerably, and by 2 years, growth in height usually continues at a fairly steady rate of approximately 2 1/2 inches per year until adolescence. No child grows at a perfectly steady rate throughout this period of childhood, however. Weeks or months of slightly slower growth alternate with mini growth spurts in normal children. Kids actually tend to grow a bit faster in the spring than during other times of the year. A major growth spurt occurs at the time of puberty. Around ages 8 to 13 in girls and 10 to 15 in boys, kids enter puberty, which lasts from about 2 to 5 years. By the time girls reach age 15 and boys reach age 16 or 17, the growth associated with puberty will have ended for most teens and they will have reached physical maturity.

Tanzanias Climate Essay -- Tourism Africa Global Warming Environment

Tanzania's Climate Tanzania represents a wealth of ecological diversity, ethnic diversity, and geographical diversity. It contains both the tallest mountain in Africa as well as the largest lake, and is a tourist hotspot for safaris and expeditions to Mt. Kilimanjaro. The citizens of Tanzania are utterly dependent on the weather for their two major businesses, agriculture and tourism. Thus, the climate of Tanzania is worth examining in greater detail. Tanzania has two distinct seasons, wet and dry. However, the northern region of Tanzania can experience two wet seasons, the longest of which spans from March to May and the shortest from November to December. The March to May period is known as â€Å"the long rains†, during which excessive rainfall occurs. The shorter period from November to December is known as â€Å"the short rains†, where rainfall occurs intermittently and may last into January. The rest of the country experiences one wet season from November to May. Since Tanzania is located in the Southern hemisphere, December to March can be considered the country’s summer, and June to September its winter. The seasons are â€Å"in fact the transition between the two main trade wind systems which dominate at different times of the year; the northeasterly trades between December and March, and the southeasterlies between June and September† (Sumner 53-66). Caused by the highly cyclic weather patterns of the intertropical convergence zone, these trade winds are the main factor in determining the change of seasons and are abetted by the very geography of Tanzania. The flow of air over the East African plateau causes the formation of the Southerly Jet which in turn regulates the Indian monsoon season. The jet flows in parallel to Ta... ...does not bode well for its inhabitants. If remedial measures are not taken, Tanzania’s economy and quality of life will suffer greatly in the near future, and we as a planet will suffer greater consequences in the far future due to the rising temperature of the Earth. Works Cited: Alverson, Keith, et al. "A Global Paleoclimate Observing System." Science 293.5527 (2001): 47-8. Nieuwolt, S. "Rainstorm Distributions in Tanzania." Geografiska Annaler.Series A, Physical Geography 56.3/4 (1974): 241-50. Sumner, G. N. "Daily Rainfall Variability in Coastal Tanzania." Geografiska Annaler.Series A, Physical Geography 65.1/2 (1983): 53-66. Zhou, Guofa, et al. "Association between Climate Variability and Malaria Epidemics in the East African Highlands." Proceedings of the National Academy of Sciences of the United States of America 101.8 (2004): 2375-80.